And all that will change when the men from Europe arrive here, when they arrive with their guests...
Measles. Smallpox. Typhoid. Cholera. Malaria. Bubonic Plague. Typhus. Yellow Fever. Diptheria. Whooping Cough. Tuberculosis. Gonorrhea. Tetanus. Chicken Pox. Herpes. Meningitis. Hepatitis. Encephalitis. Childbed Fever. And more, too many more to name...
All those will be gifts from the Old World men to us. In many cases we'll receive these gifts before we ever see a man of the Old World. Our bodies will not know them or how to fight them. Our physicians will not have seen them or know how to treat them, and many will not live long enough to devise treatments.

Tlaloc, Lord of the Storm